BIOHYBRID MATERIALS CHEMISTRY LABORATORY

(62) Taira Sato, Yuki Shirosaki, Sho Oshima, Kanji Tsuru, Yoshihisa Koyama, Mamoru Aizawa, Masanori Kikuchi, “Initial bone tissue reactions of hydroxyapatite/collagen–(3-glycidoxypropyl)trimethoxysilane injectable bone paste”, Journal of Biomedical Materials Research: Part B, 112[8], e35451 (2024). July

(61) Supakorn Boonyuen, Shanmugam Paramasivam, Rajan Ramachandran, Tossapon Phromsatit, Thapong Teerawatananond, Supawan Tantayanon, Premjit Arpornmaeklong, Yuki Shirosaki, “Exploring copper (II) porphyrin complexes and their derivatives for electrochemical analysis and biological assessment in the study of breast cancer (MCF-7) cell lines”, Environmental Research, 250[1], 118489 (2024). February

(60) Yuki Shirosaki, Federica Fregnan, Luisa Muratori, Saki Yasutomi, Stefano Geuna, Stefania Raimondo, “The impact of the molecular weight of degradation products with silicon from porous chitosan-siloxane hybrids on neuronal cell behavior”, Polymers, 15[15], 3272-3285 (2023). August

(59) Kosei Hattori, Satoshi Hayakawa, Yuki Shirosaki, “Effects of the silicon-containing chemical species dissolved from chitosan-siloxane hybrids on nerve cells”, Journal of Sol-Gel Science and Technology, 104[3], 606- 661 (2022). May

(58) Yuki Shirosaki, Yasuyo Tsukatani, Kohei Okamoto, Satoshi Hayakawa, Akiyoshi Osaka, “Preparation and drug release profile of chitosan–siloxane hybrid capsules coated with hydroxyapatite”, Pharmaceutics, 14[5], 1111-1120 (2022). May

(57) Ashreen Norman, Ahmad Kamil Mohd, Jaaffar, Nazzatush Shimar Jamaludin, Yuki Shirosaki, Norazalina Saad, Che Azurahanim Che Abdullah, “Cocoa pod husks as precursors for biosynthesis of carbon dots as potential bioimaging tool”, International Journal of Nanoscience and Nanotechnology, 18[1], 79-92 (2022). March

(56) Emmellie Laura Albert, Siti Norzulfikaini Yaacob, Ghazaleh Bahmanrokh, Toshiki Miyazaki, Yuki Shirosaki, Che Azurahanim Che Abdullah, “Preparation and characterization of encapsulated tamoxifen citrate-magnetite nanoparticle via oil in water emulsion evaporation technique”, Nanomedicine Research Journal, 6[4], 337-346 (2021). November

(55) Tossapon Phromsatit, Premjit Arpornmaeklong, Yuki Shirosaki, Thapong Teerawatananond, Jundee Rabablert, Supakorn Boonyuen, “Synthesis and cytotoxicity study of gold(III) porphyrin complexes and their derivative in breast cancer cells”, Journal of Saudi Chemical Society, 25, 101366-101373 (2021). October

(54) Kazutaka Kumamoto, Toshinari Maeda, Satoshi Hayakawa, Nurul Asyifah Binti Mustapha, Meng-Jiy Wang, Yuki Shirosaki, “Antibacterial chitosan nanofiber thin films with bacitracin zinc salt”, Polymers, 13[7], 1104-1119 (2021). April

(53) Nur Sharmila Sharip, Hidayah Ariffin, Tengku Arisyah Tengku Yasim-Anuar, Yoshito Andou, Yuki Shirosaki, Mohammad Jawaid, Paridah Md Tahir, Nor Azowa Ibrahim, “Melt-vs. non-melt blending of complexly processable ultra-high molecular weight polyethylene/cellulose nanofiber bionanocomposite”, Polymers, 13[3], 404-419 (2021). January

(52) Yuki Shirosaki, Toshinobu Okabayashi, Saki Yasutomi, “Silane coupling agent modifies the mechanical properties of a chitosan microfiber”, Molecules, 25[22], 5292-5301 (2020). November

(51) Nur Sharmila Sharip, Hidayah Ariffin, Yoshito Andou, Yuki Shirosaki, Ezyana Kamal Bahrin, Mohammad Jawaid, Paridah Md Tahir, Nor Azowa Ibrahim, “Process optimization of ultra-high molecular weight polyethylene/cellulose nanofiber bionanocomposites in triple screw kneading extruder by response surface methodology”, Molecules, 25[19], 4498-4515 (2020). September

(50) Saitong Muneekaew, Kai-Cheng Chang, Alfin Kurniawan, Yuki Shirosaki, Meng-Jiy Wang, “Microwave plasma treated composites of Cu/Cu2O nanoparticles on electrospun poly(N-vinylpyrrolidone) fibers as highly effective photocatalysts for reduction of organic dyes and 4-nitrophenol”, Journal of the Taiwan Institute of Chemical Engineers, 107, 171-181 (2020). February

(49) Yuki Shirosaki, Manato Nakatsukasa, Saki Yasutomi, Susana Cruz-Neves, Satoshi Hayakawa, Akiyoshi Osaka, Toshinari Maeda, Toshiki Miyazaki, “Cytocompatible and antibacterial properties of chitosan−siloxane hybrid spheres”, Polymers, 11[10], 1676-1686 (2019). October

(48) Toshiki Miyazaki, Akiko Iwanaga, Yuki Shirosaki, Masakazu Kawashita, “In situ synthesis of magnetc iron oxide nanoparticles in chitosan hydrogels as a reaction field: effect of cross-linking density”, Colloids and Surfaces B: Biointerfaces, 179, 334-339 (2019). July

(47) Toshiki Miyazaki, Takashi Arii, Yuki Shirosaki, “Control of crystalline phase and morphology pf calcium carbonate by electrolysis: effects of current and temperature”, Ceramics International, 45[11], 14039-14044 (2019). May

(46) Emmellie Laura Albert, Che Azurahanim Che Abdullah, Yuki Shirosaki, “Synthesis and characterization of graphene oxide functionalized with magnetic nanoparticle via simple emulsion method”, Results in Physics, 11, 944-950 (2018). December

(45) Taira Sato, Yuki Shirosaki, Masaki Nagaya, Yoshinori Asano, Kazuaki Nakano, Hiroshi Nagashima, Mamoru Aizawa, Masanori Kikuchi, “Preparation of anti-decay self-setting paste of hydroxyapatite/collagen utilizing (3-glycidoxypropyl)trimethoxysilane”, Journal of Asian Ceramic Societies, 6[4], 322-331 (2018). October

(44) Toshiki Miyazaki, Masaya Sueoka, Yuki Shirosaki, Nobuya Shinozaki, Takanobu Shiraishi, “Development of hafnium metal and titanium-hafnium alloys having apatite-forming ability by chemical surface modification”, Journal of Biomedical Materials Research: Part B Applied Biomaterials, 106[7], 2519-2523 (2018). October

(43) Yuki Shirosaki, Motomasa Furuse, Takuji Asano, Yoshihiko Kinoshita, Toshihiko Kuroiwa, “Skull bone regeneration using chitosan-siloxane porous hybrids ~long-term implantation~”, Pharmaceutics, 10[2], 70-78 (2018). June

(42) Ryo Hamai, Yuki Shirosaki, Toshiki Miyazaki, “Structural effects of sulfur-containing functional groups on apatite formation on Ca2 -modified copolymers in a simulated body environment”, ACS Omega, 3[5], 5627-5633 (2018). May

(41) Emmellie Laura Albert, Yuki Shirosaki, Che Azurahanim Che Abdullah, “Drug release and kinetic study of tamoxifen citrate conjugated with magnetite nanoparticle for drug delivery application”, International Journal of Applied Engineering Research, 13[7], 5360-5369 (2018). April

(40) Ryo Hamai, Hirotaka Maeda, Hikaru Sawai, Yuki Shirosaki, Toshihiro Kasuga, Toshiki Miyazaki, “Structural effects of phosphate groups on apatite formation in copolymer modified with Ca² in a simulated body fluid”, Journal of Materials Chemistry B, 6[1], 174-182 (2018). January

(39) Toshiki Miyazaki, Takashi Sasaki, Yuki Shirosaki, Ken’ichi Yokoyama, Masakazu Kawashita, “Effect of metallographic structure and machining process on the apatite-forming ability of sodium hydroxide- and heat-treated titanium”, Bio-Medical Materials and Engineering, 29[1], 109-118 (2018). January

(38) Susana Neves, Yuki Shirosaki, Toshiki Miyazaki, Satoshi Hayakawa, “Characterization and degradation study of chitosan-siloxane hybrid microspheres synthesized using a microfluidic approach”, Materials Science & Engineering C, 81, 571-579 (2017). December

(37) Takuma Okada, Yuta Nobunaga, Toshiisa Konishi, Tomohiko Yoshioka, Satoshi Hayakawa, Maria A. Lopes, Toshiki Miyazaki, Yuki Shirosaki, “Preparation of chitosan-hydroxyapatite composite mono-fiber using coagulation method and their mechanical properties”, Carbohydrate Polymers, 175, 355-360 (2017). November

(36) Ryo Hamai, Yuki Shirosaki, Toshiki Miyazaki, “Apatite formation on a hydrogel containing sulfinic acid group under physiological conditions”, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 105[7], 1924-1929 (2017). October

(35) Marta Laranjeira, Yuki Shirosaki, Saki Yoshimatsu Yasutomi, Toshiki Miyazaki, Fernando J. Monteiro, “Enhanced biosafety of silica coated gadolinium based nanoparticles”, Journal of Materials Science: Materials in Medicine, 28[3], 1-13 (2017). February

(34) Toshiki Miyazaki, Chisato Matsunami, Yuki Shirosaki, “Bioactive carbon-PEEK composites prepared by chemical surface treatment”, Materials Science and Engineering C, 70, Part 1, 71-75 (2017). January

(33) Ryo Hamai, Yuki Shirosaki, Toshiki Miyazaki, “Apatite-forming ability of vinylphosphonic acid-based copolymer in simulated body fluid: effects of phosphate group content” Journal of Materials Science: Materials in Medicine, 27[10], 152-159 (2016). October

(32) Yoshimitsu Kuwahara, Toshiki Miyazaki, Yuki Shirosaki, Gengci Liu, Masakazu Kawashita, “Structure of organic additives modified magnetite nanoparticles”, Ceramics International, 42[5], 6000-6004 (2016). April

(31) Yuki Shirosaki, Motomasa Furuse, Takuji Asano, Yoshihiko Kinoshita, Toshiki Miyazaki, Toshihiko Kuroiwa, “Use of chitosan-siloxane porous hybrid scaffold as novel burr hole covers”, Letters in Applied NanoBioScience, 5[1], 342-345 (2016). March

(30) Ryo Hamai, Yuki Shirosaki, Toshiki Miyazaki, “Biomineralization behavior of a vinylphosphonic acid-based copolymer added with polymerization accelerator in simulated body fluid”, Journal of Asian Ceramic Societies, 3[4], 407-411 (2015). December

(29) Chao Liu, Chisato Matsunami, Yuki Shirosaki, Toshiki Miyazaki, “Bioactive Co-Cr alloy for biomedical applications prepared by surface modification using self-assembled monolayers and poly-γ-glutamic acid”, Dental Materials Journal, 34[5], 707-712 (2015). October

(28) Satoshi Hayakawa, Kanji Tsuru, Yuki Shirosaki, Keita Uetsuki, Keisuke Akasaka, Akiyoshi Osaka, “Calcium phosphate crystallization on titania in Kokubo solution flowing throw narrow space”, Journal of Materials Science: Materials in Medicine, 26[8], 222, Page 13 (2015). August

(27) Satoshi Hayakawa, Yuko Matsumoto, Keita Uetsuki, Yuki Shirosaki, Akiyoshi Osaka, “In vitro apatite formation on nano-crystalline titania layer aligned parallel to Ti6Al4V alloy substrates with sub-millimeter gap”, Journal of Materials Science: Materials in Medicine, 26[6], 190, Page 8 (2015). May

(26) Jinkun Liu, Yuki Shirosaki, Toshiki Miyazaki, “Bioactive PMMA bone cement modified with combinations of phosphate group-containing monomers and calcium acetate” Journal of Biomaterials Applications, 29[9], 1296-1303 (2015). March

(25) Eiji Fujii, Koji Kawabata, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka, “Fabrication of calcium phosphate nanoparticles in a continuous flow tube reactor”, Journal of the Ceramic Society of Japan, 123[3], 101-105 (2015). March

(24) Yuki Shirosaki, Masashi Hirai, Satoshi Hayakawa, Eiji Fujii, Maria A. Lopes, José D. Santos, Akiyoshi Osaka, “Preparation and in vitro cytocompatibility of chitosan-siloxane hybrid hydrogels”, Journal of Biomedical Materials Research PartA, 103[1], 289-299 (2015). January

(23) Miguel Carvalho, Luís M. Costa, José E. Pereira, Yuki Shirosaki, Satoshi Hayakawa, José D. Santos, Stefano Geuna, Federica Fregnan, António M. Cabrita, Ana C. Maurício, Artur S. Varejão, “The role of hybrid chitosan membranes on scarring process following lumbar surgery: post-laminectomy experimental model”, Neurological Research, 37[1], 23-29 (2015). January

(22) Yuki Shirosaki, Kohei Okamoto, Satoshi Hayakawa, Akiyoshi Osaka, Takuji Asano, “Preparation of porous chitosan-siloxane hybrids coated with hydroxyapatite particles”, BioMed Research International, 2015, Article ID 392940, 6 pages (2015). January

(21) Toshiki Miyazaki, Toru Tanaka, Yuki Shirosaki, Masakazu Kawashita, “Yttrium phosphate microspheres with enriched phosphorus content prepared for radiotherapy of deep-seated cancer”, Ceramics International, 40[9], 15259-15263(2014). November

(20) Toshiki Miyazaki, Tatsuya Inoue, Yuki Shirosaki, Masakazu Kawashita, Takao Matsubara, Akihiko Matsumine, “Bisphosphonate release profiles from magnetite microspheres”, Journal of Biomaterials Applications, 29[4], 543-547 (2014). September

(19) Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka, Maria A. Lopes, José D. Santos, Stefano Geuna, Ana C. Maurício, “Challenges for nerve repair using chitosan-siloxane hybrid porous scaffolds”, BioMed Research International, 2014, Article ID 153808, 7 pages (2014). June

(18) Yoshimitsu Kuwahara, Toshiki Miyazaki, Yuki Shirosaki, Masakazu Kawashita, “Effects of organic polymer addition in magnetite synthesis on its crystalline structure”, RSC Advances, 4, 23359-23363 (2014). June

(17) Shunsuke Nishimoto, Michiaki Becchaku, Yoshikazu Kameshima, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka, Michihiro Miyake, “TiO2-based superhydrophobic-superhydrophilic pattern with an extremely high wettability contrast”, Thin Solid Films, 558[2], 221-226 (2014). February

(16) Satoshi Hayakawa, Yoshitake Masuda, Keigo Okamoto, Yuki Shirosaki, Kazumi Kato, Akiyoshi Osaka, “Liquid phase deposited titania coating to enable in vitro apatite formation on Ti6Al4V alloy”, Journal of Materials Science: Materials in Medicine, 25, 375-381 (2014). February

(15) Toshiki Miyazaki, Takajin Suda, Yuki Shirosaki, Masakazu Kawashita, “Fabrication of yttrium phosphate microcapsules by an emulsion route for in situ cancer radiotherapy”, Journal of Medical and Biological Engineering, 34[1], 14-17 (2014). February

(14) Jo Duncan, James F. MacDonald, John V. Hanna, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka, Janet M.S. Skakle, Iain R. Gibson, “The role of the chemical composition of monetite on the synthesis and properties of α-tricalcium phosphate”, Materials Science and Engineering C, 34, 123-129 (2014). January

(13) Kanji Tsuru, Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka, "Sol-gel-derived silicate nano-hybrids for biomedical applications", Biological and Pharmaceutical Bulletin, 36[11], 1683-1687 (2013). November

(12) Toshiki Miyazaki, Kunio Ishikawa, Yuki Shirosaki, Chikara Ohtsuki, "Organic-inorganic composites designed for biomedical applications", Biological and Pharmaceutical Bulletin, 36[11], 1670-1675 (2013). November

(11) Taira Sato, Akinori Kochi, Yuki Shirosaki, Satoshi Hayakawa, Mamoru Aizawa, Akiyoshi Osaka, Masanori Kikuchi, “Preparation of injectable hydroxyapatite/collagen paste using sodium alginate and influence of additives”, Journal of the Ceramic Society of Japan, 121[9], 775-781 (2013). September

(10) Toshiki Miyazaki, Akimasa Kuramoto, Atsuhide Hirakawa, Yuki Shirosaki, Chikara Ohtsuki, “Biomineralization on chemically synthesized collagen containing immobilized poly-γ-glutamic acid”, Dental Materials Journal, 30[4], 544-549 (2013). August

(9) Yuki Shirosaki, Tomoyuki Okayama, Kanji Tsuru, Satoshi Hayakawa, Akiyoshi Osaka, “In vitro bioactivity and MG63 cytocompatibility of chitosan-silicate hybrids”, International Journal of Materials and Chemistry, 3(3A), 1-7 (2013). June 

(8) Jinkun Liu, Yoshimitsu Kuwahara,Yuki Shirosaki, Toshiki Miyazaki, “The investigation of bioactivity and mechanical properties of glass ionomer cements prepared from Al2O3-SiO2 glass and poly(γ-glutamic acid)", Journal of Nanomaterials, 2013, Article ID 168409, 6 pages (2013). June

(7) Jie Li, Satoshi Hayakawa,Yuki Shirosaki, Akiyoshi Osaka, “Revisiting structure of silica gels from water glass: an 1H and 29Si MAS and CP-MAS NMR study”, Journal of Sol-Gel Science and Technology, 65[2], 135-142 (2013). March

(6) Keita Uetsuki, Shinsuke Nakai,Yuki Shirosaki, Satoshi Hayakawa, Akiyoshi Osaka, "Nucleation and growth of apatite on an anatase layer irradiated with UV light under different environmental conditions", Journal of Biomedical Materials Research A, 101A[3], 712-719 (2013). March

(5) Satoshi Hayakawa, Tomoko Kanaya, Kanji Tsuru,Yuki Shirosaki, Akiyoshi Osaka, Eiji Fujii, Koji Kawabata, Georgiana Gasqueres, Christian Bonhomme, Florence Babonneau, Christian Jäger, Hans-Joachim Kleebe, “Heterogeneous structure and in vitro degradation behavior of wet-chemically derived nanocrystalline silicon-containing hydroxyapatite particles”, Acta Biomaterialia, 9[1], 4856-4867 (2013). January

(4) Yuki Shirosaki, “Preparation of organic-inorganic hybrids with silicate network for the medical applications”, Journal of the Ceramic Society of Japan, 120[12], 555-559 (2012). December

(3) Yuki Shirosaki, Hiroki Yoshihara, Song Chen, Mark Blevins, Yuri Nakamura, Nobutaka Hanagata, Satoshi Hayakawa, Artemis Stamboulis, Akiyoshi Osaka, “Electrospun poly(vinyl alcohol) as a template of silica hollow and solid micro-fibrous mats”, Journal of the Ceramic Society of Japan, 120[11], 520-524 (2012). November

(2) Andrea Gärtner, Tiago Pereira, Maria J. Simões, Paulo A.S. Armada-da Silva, Miguel L. França, Rosa Sousa, Simone Bompasso, Stefania Raimondo, Yuki Shirosaki, Yuri Nakamura, Satoshi Hayakawa, Akiyoshi Osaka, Beatriz Porto, Ana L. Luís, Artur S.P. Varejão, Ana C. Maurício, “Use of hybrid chitosan membranes and human mesenchymal stem cells from the Wharton jelly of umbilical cord for promoting nerve regeneration in an axonotmesis rat model”, Neural Regeneration Research, 7[29], 2247-2258 (2012). October

(1) Jie Li, Yuki Shirosaki, Satoshi Hayakawa, Artemis Stamboulis, Akiyoshi Osaka, “Sol-gel preparation of apatite-coated silica macrospheres from water glass and their adsorption of bovine serum albumin and lysozyme”, Journal of the Ceramic Society of Japan, 120[9], 355-361 (2012). September